Chemical oxidation is carried out by adding chemical reagents at atmospheric pressure, which is mainly applied to carbonaceous and non typical pyrite gold ores. Chemical reagents are mainly ozone, peroxide, potassium permanganate, chlorine, manganese dioxide, perchlorate, hypochlorite etc.. There are (chlorination treatment of carbon blame leaching of gold ore and the reduction method (processing) of pyrite and arsenopyrite) two.

2003年8月，我国西南某金矿建成了一座300t/d采用化学碱浸预处理一氰化提金工艺的工厂，采用氢氧化钠直接氧化分解黄铁矿、磁黄铁矿、毒砂。在难处理金矿的各种预处理工艺中，碱浸预处理的基建投资是最低的，一由于浸出在碱性溶液中进行，对设备的防腐要求比较低。但浸出要消耗大量的氢氧化钠，故生产成本比较高。这种工艺直接处理原矿，适宜于矿石中金品位高，含硫很低，脉石不耗碱，.而金又主要赋存在硫化物中的矿山采用。

In August 2003, a gold mine of Southwest China built a 300t / D by alkali chemical leaching pretreatment - cyanide leaching process factory, the direct oxidation of sodium hydroxide decomposition of pyrite, pyrrhotite, arsenopyrite. In the pretreatment process of refractory gold ore, alkali leaching pretreatment of capital construction investment is the lowest, because of leaching in alkaline solution, the corrosion protection requirements of equipment is relatively low. However, it consumes a lot of sodium hydroxide, so the production cost is high. This process directly processing ore, suitable for high grade of gold in ores, sulfur content is very low, gangue no alkali consumption. And gold and is hosted mainly exist in sulfide mines using.

微波氧化是采用超高频电磁波对难浸金矿石进行预处理，目前尚无工业应用。

Microwave oxidation is the use of ultra high frequency electromagnetic wave of refractory gold ore pretreatment, there is no industrial application.